Literature summary for 5.6.2.1 extracted from

Rahier, N.J.; Eisenhauer, B.M.; Gao, R.; Thomas, S.J.; Hecht, S.M.
On the role of E-ring oxygen atoms in the binding of camptothecin to the topoisomerase I-DNA covalent binary complex (2005), Bioorg. Med. Chem., 13, 1381-1386.

Inhibitors

Inhibitors	Comment	Organism
20(S)-camptothecin	-	Homo sapiens
20-mercaptocamptothecin	weak	Homo sapiens
additional information	10,21-dimercaptocamptothecin is not cytotoxic	Homo sapiens

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

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Release 2023.1 (January 2023)