Literature summary for 5.6.2.1 extracted from

Belova, G.I.; Prasad, R.; Kozyavkin, S.A.; Lake, J.A.; Wilson, S.H.; Slesarev, A.I.
A type IB topoisomerase with DNA repair activities (2001), Proc. Natl. Acad. Sci. USA, 98, 6015-6020.

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Cloned(Commentary)

Cloned (Comment)	Organism
-	Methanopyrus kandleri

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
additional information	Methanopyrus kandleri	topo V contains a signature motif of leucine-responsive regulatory proteins and therefore might also act as a transcriptional regulator, in addition to being a topoisomerase and an apurinic/apyrimidinic lyase	?	-	?

Organism

Organism	UniProt	Comment	Textmining
Methanopyrus kandleri	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
additional information	topo V contains a signature motif of leucine-responsive regulatory proteins and therefore might also act as a transcriptional regulator, in addition to being a topoisomerase and an apurinic/apyrimidinic lyase	Methanopyrus kandleri	?	-	?

Synonyms

Synonyms	Comment	Organism
topo V	-	Methanopyrus kandleri
type IB topoisomerase V	-	Methanopyrus kandleri

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Release 2023.1 (January 2023)