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Literature summary for 5.6.2.1 extracted from

  • Guichard, S.; Hennebelle, I.; Bugat, R.; Canal, P.
    Cellular interactions of 5-fluorouracil and the camptothecin analogue CPT-11 (irinotecan) in human colorectal carcinoma cell line (1998), Biochem. Pharmacol., 55, 667-676.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
7-ethyl-10-[4-(1-piperidino)-1-piperidino]-carbonyloxy-camptothecin strong synergism between irinotecan and 5-fluorouracil Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
HT-29 cell
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
supercoiled DNA relaxation Homo sapiens relaxed closed circular DNA
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