Application | Comment | Organism |
---|---|---|
pharmacology | target of a novel class of anticancer drugs the camptothecins | eukaryota |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | eukaryota | role of topoisomerase I in DNA replication, transcription and recombination | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
eukaryota | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | role of topoisomerase I in DNA replication, transcription and recombination | eukaryota | ? | - |
? | |
supercoiled DNA | relaxation | eukaryota | relaxed closed circular DNA | - |
? |