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Literature summary for 5.6.2.1 extracted from

  • Hyder, S.M.; Baldi, A.; Crespi, M.; Wittliff, J.L.
    Rapid purification of topoisomerase I from human breast cancer cells by high-performance liquid chromatography (1986), J. Chromatogr., 359, 433-447.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens enzyme controls the topological state of DNA ?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
partial Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
breast adenocarcinoma cell
-
Homo sapiens
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information enzyme controls the topological state of DNA Homo sapiens ?
-
?
supercoiled DNA negatively supercoiled plasmid pBR322 DNA Homo sapiens relaxed closed circular DNA
-
?
supercoiled DNA relaxation Homo sapiens relaxed closed circular DNA
-
?