Inhibitors | Comment | Organism | Structure |
---|---|---|---|
poly(dG) | not by other homopolymerical deoxyribonucleotides | Rattus norvegicus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
K+ | stimulates, optimal concentration: 175-200 mM. K+ stimulates 10-15% more effectively than Na+ | Rattus norvegicus | |
Na+ | stimulates, optimal concentration: 175-200 mM | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
cerebral cortex | neuron | Rattus norvegicus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
- |
Rattus norvegicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
supercoiled DNA | relaxation | Rattus norvegicus | relaxed closed circular DNA | - |
? | |
supercoiled DNA | enzyme links to the 3' ends of the broken DNA strands | Rattus norvegicus | relaxed closed circular DNA | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | proteins with MW 75000, 83000, 91000 or 100000 with DNA topoisomerase I activity are detected | Rattus norvegicus |