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Literature summary for 5.6.1.8 extracted from
- Bovine platelet myosin. Properties of Mg- and Ca-ATPase (1978), J. Biochem., 84, 607-616.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| actin | - |
Bos taurus |  |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.0001 | - |
ATP | Mg-ATPase, 0.6 M KCl | Bos taurus | |
| 0.01 | - |
ATP | Ca-ATPase, 2.0 mM Ca2+ | Bos taurus | |
| 0.25 | - |
ATP | K+EDTA-ATPase, 1 mM EDTA | Bos taurus | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + H2O + myosin bound to actin filament at position n | Bos taurus | nucleoside triphosphates are hydrolyzed in the following order: GTP, ITP, CTP, ATP, UTP | ADP + phosphate + myosin bound to actin filament at position n+1 | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bos taurus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| platelet | - |
Bos taurus | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 0.0003 | - |
substrate UTP, basal myosin ATPase, 0.6 M KCl, 2 mM MgCl2, pH 7 | Bos taurus |
| 0.003 | - |
substrate ATP, basal myosin ATPase, 0.6 M KCl, 2 mM MgCl2, pH 7 | Bos taurus |
| 0.004 | - |
substrate CTP, basal myosin ATPase, 0.6 M KCl, 2 mM MgCl2, pH 7 | Bos taurus |
| 0.005 | - |
substrate ITP, basal myosin ATPase, 0.6 M KCl, 2 mM MgCl2, pH 7 | Bos taurus |
| 0.007 | - |
substrate GTP, basal myosin ATPase, 0.6 M KCl, 2 mM MgCl2, pH 7 | Bos taurus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + H2O + myosin bound to actin filament at position n | nucleoside triphosphates are hydrolyzed in decreasing order: GTP, ITP, CTP, ATP, UTP | Bos taurus | ADP + phosphate + myosin bound to actin filament at position n+1 | - |
? | |
| ATP + H2O + myosin bound to actin filament at position n | nucleoside triphosphates are hydrolyzed in the following order: GTP, ITP, CTP, ATP, UTP | Bos taurus | ADP + phosphate + myosin bound to actin filament at position n+1 | - |
? | |
| CTP + H2O + myosin bound to actin filament at position n | - |
Bos taurus | CDP + phosphate + myosin bound to actin filament at position n+1 | - |
? | |
| GTP + H2O + myosin bound to actin filament at position n | - |
Bos taurus | GDP + phosphate + myosin bound to actin filament at position n+1 | - |
? | |
| ITP + H2O + myosin bound to actin filament at position n | - |
Bos taurus | IDP + phosphate + myosin bound to actin filament at position n+1 | - |
? | |
| UTP + H2O + myosin bound to actin filament at position n | - |
Bos taurus | UDP + phosphate + myosin bound to actin filament at position n+1 | - |
? | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 5 | - |
platelet myosin, Mg-ATPase at 25°C, high ionic strength, 0.6 M KCl | Bos taurus |
| 9.5 | - |
platelet myosin, Mg-ATPase at 25°C, high ionic strength, 0.6 M KCl | Bos taurus |
| 9.5 | - |
platelet myosin, Ca-ATPase at 25°C, high ionic strength, 0.6 M KCl | Bos taurus |
pH Range
| pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|
| 5 | 10 | Mg-ATPase, acidic maximum at pH 5.0, alkaline maximum at pH 9.5, high ionic strength, 0.6 M KCl | Bos taurus |
| 5 | 10 | Ca-ATPase, acidic maximum at pH 5.0, alkaline maximum (higher) at pH 9.5, high ionic strength, 0.6 M KCl | Bos taurus |
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