Activating Compound | Comment | Organism | Structure |
---|---|---|---|
actin | - |
Gallus gallus | |
actin | - |
Oryctolagus cuniculus | |
actin | - |
Dictyostelium sp. |
Protein Variants | Comment | Organism |
---|---|---|
additional information | myosin loop 2 replaced by rabbit skeletal or smooth muscle loop 2 | Dictyostelium sp. |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.02 | - |
ATP | chimeric myosin, Dictyostelium myosin loop 2 replaced by rabbit skeletal myosin loop 2, actin activated | Oryctolagus cuniculus | |
0.02 | - |
ATP | chimeric myosin, Dictyostelium myosin loop 2 replaced by rabbit skeletal myosin loop 2, actin activated | Dictyostelium sp. | |
0.043 | - |
ATP | subfragment 1 | Dictyostelium sp. | |
0.06 | - |
ATP | chimeric myosin, Dictyostelium myosin loop 2 replaced by chicken smooth muscle myosin loop 2, actin activated | Oryctolagus cuniculus | |
0.06 | - |
ATP | chimeric myosin, Dictyostelium myosin loop 2 replaced by chicken smooth muscle myosin loop 2, actin activated | Dictyostelium sp. |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + H2O + myosin bound to actin filament at position n | Gallus gallus | - |
ADP + phosphate + myosin bound to actin filament at position n+1 | - |
? | |
ATP + H2O + myosin bound to actin filament at position n | Oryctolagus cuniculus | - |
ADP + phosphate + myosin bound to actin filament at position n+1 | - |
? | |
ATP + H2O + myosin bound to actin filament at position n | Dictyostelium sp. | - |
ADP + phosphate + myosin bound to actin filament at position n+1 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Dictyostelium sp. | - |
- |
- |
Gallus gallus | - |
chicken | - |
Oryctolagus cuniculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
gizzard smooth muscle | - |
Gallus gallus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + H2O + myosin bound to actin filament at position n | - |
Gallus gallus | ADP + phosphate + myosin bound to actin filament at position n+1 | - |
? | |
ATP + H2O + myosin bound to actin filament at position n | - |
Oryctolagus cuniculus | ADP + phosphate + myosin bound to actin filament at position n+1 | - |
? | |
ATP + H2O + myosin bound to actin filament at position n | - |
Dictyostelium sp. | ADP + phosphate + myosin bound to actin filament at position n+1 | - |
? |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.1 | - |
ATP | basal activity | Dictyostelium sp. | |
0.95 | - |
ATP | smooth muscle myosin | Oryctolagus cuniculus | |
1.2 | - |
ATP | chimeric myosin, Dictyostelium myosin loop 2 replaced by chicken smooth muscle myosin loop 2, actin activated | Dictyostelium sp. | |
3 | - |
ATP | actin activated | Dictyostelium sp. | |
3.1 | - |
ATP | myosin subfragment 1, actin activated | Dictyostelium sp. | |
5.7 | - |
ATP | chimeric myosin, Dictyostelium myosin loop 2 replaced by rabbit skeletal myosin loop 2, actin activated | Dictyostelium sp. | |
20 | - |
ATP | skeletal muscle myosin, actin-activated | Oryctolagus cuniculus |