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Literature summary for 5.6.1.7 extracted from
- The GroEL chaperonin a protein machine with pistons driven by ATP binding and hydrolysis (2018), Philos. Trans. R. Soc. Lond. B Biol. Sci., 373, 20170179 .
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| D52A/D358A | ATPase-deficient mutant | Escherichia coli |
| D83A/R197A | allosterically compromised mutant | Escherichia coli |
| K105A | allosterically compromised mutant | Escherichia coli |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + H2O + a folded polypeptide | Escherichia coli | - |
ADP + phosphate + an unfolded polypeptide | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Escherichia coli | P0A6F5 | - |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + H2O + a folded polypeptide | - |
Escherichia coli | ADP + phosphate + an unfolded polypeptide | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| tetradecamer | - |
Escherichia coli |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| chaperonin | - |
Escherichia coli |
| GroEl | - |
Escherichia coli |
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Release 2023.1 (January 2023)
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