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Literature summary for 5.6.1.7 extracted from

  • Chaudhuri, T.K.; Verma, V.K.; Maheshwari, A.
    GroEL assisted folding of large polypeptide substrates in Escherichia coli: Present scenario and assignments for the future (2009), Prog. Biophys. Mol. Biol., 99, 42-50.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
GroES dependent on substrate if complete chaperonin system GroEL-GroES and ATP is required Escherichia coli

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O + a folded polypeptide Escherichia coli aconitase B, bind transiently to GroEL and probably doesn´t require ATP and GroES ADP + phosphate + an unfolded polypeptide
-
?
ATP + H2O + a folded polypeptide Escherichia coli MetE, bind transiently to GroEL and probably doesn´t require ATP and GroES ADP + phosphate + an unfolded polypeptide
-
?

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + a folded polypeptide aconitase B, bind transiently to GroEL and probably doesn´t require ATP and GroES Escherichia coli ADP + phosphate + an unfolded polypeptide
-
?
ATP + H2O + a folded polypeptide MetE, bind transiently to GroEL and probably doesn´t require ATP and GroES Escherichia coli ADP + phosphate + an unfolded polypeptide
-
?
ATP + H2O + a folded polypeptide aconitase, requires GroEL, co-chaperonin GroES and ATP for complete folding Escherichia coli ADP + phosphate + an unfolded polypeptide
-
?
ATP + H2O + a folded polypeptide beta-galactosidase, bind transiently to GroEL and probably doesn´t require ATP and GroES Escherichia coli ADP + phosphate + an unfolded polypeptide
-
?
ATP + H2O + a folded polypeptide decarboxylase component E1, requires GroEL, co-chaperonin GroES and ATP for complete folding Escherichia coli ADP + phosphate + an unfolded polypeptide
-
?
ATP + H2O + a folded polypeptide dependent on protein if ATP release substrate from GroEL or if complete chaperonin system GroEL-GroES and ATP is required Escherichia coli ADP + phosphate + an unfolded polypeptide
-
?
ATP + H2O + a folded polypeptide green fluorescent protein, requires GroEL, co-chaperonin GroES and ATP for complete folding Escherichia coli ADP + phosphate + an unfolded polypeptide
-
?
ATP + H2O + a folded polypeptide malate dehydrogenase Escherichia coli ADP + phosphate + an unfolded polypeptide
-
?
ATP + H2O + a folded polypeptide maltodextrin glucosidase, requires GroEL, co-chaperonin GroES and ATP for complete folding Escherichia coli ADP + phosphate + an unfolded polypeptide
-
?
ATP + H2O + a folded polypeptide P22 tail spike protein, interacts with GroEL and gets released by action of nucleotide alone Escherichia coli ADP + phosphate + an unfolded polypeptide
-
?
ATP + H2O + a folded polypeptide phytochrome photoreceptor, interacts with GroEL and gets released by action of nucleotide alone Escherichia coli ADP + phosphate + an unfolded polypeptide
-
?
ATP + H2O + a folded polypeptide rhodanese Escherichia coli ADP + phosphate + an unfolded polypeptide
-
?
ATP + H2O + a folded polypeptide RUBISCO, requires GroEL, co-chaperonin GroES and ATP for complete folding Escherichia coli ADP + phosphate + an unfolded polypeptide
-
?

Subunits

Subunits Comment Organism
heptamer GroES Escherichia coli
homotetradecamer GroEL Escherichia coli

Synonyms

Synonyms Comment Organism
chaperonin GroEL
-
Escherichia coli
co-chaperonin GroES
-
Escherichia coli
GroEL-GroES
-
Escherichia coli