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Literature summary for 5.6.1.6 extracted from
- Molecular dynamics simulation study on the structural instability of the most common cystic fibrosis-associated mutant DELTAF508-CFTR (2018), Biophys. Physicobiol., 15, 33-44 .
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| DELTAF508 | the deletion mutation is associated with cystic fibrosis | Homo sapiens |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + H2O + closed Cl- channel | Homo sapiens | - |
ADP + phosphate + open Cl- channel | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + H2O + closed Cl- channel | - |
Homo sapiens | ADP + phosphate + open Cl- channel | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| CFTR | - |
Homo sapiens |
| cystic fibrosis transmembrane conductance regulator | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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