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Literature summary for 5.6.1.6 extracted from
- Control of CFTR chloride conductance by ATP levels through non-hydrolytic binding (1992), Nature, 360, 79-81.
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + H2O + closed Cl- channel | Homo sapiens | small-conductance chloride channel, direct coupling between cellular ATP levels and chloride channel activity may be an adaptive mechanism to protect the tissue from damage resulting from excessive energy depletion | ADP + phosphate + open Cl- channel | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + H2O + closed Cl- channel | chloride channel | Homo sapiens | ADP + phosphate + open Cl- channel | - |
? | |
| ATP + H2O + closed Cl- channel | small-conductance chloride channel, direct coupling between cellular ATP levels and chloride channel activity may be an adaptive mechanism to protect the tissue from damage resulting from excessive energy depletion | Homo sapiens | ADP + phosphate + open Cl- channel | - |
? | |
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