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Literature summary for 5.6.1.6 extracted from

  • Naren, A.P.; Di, A.; Cormet-Boyaka, E.; Boyaka, P.N.; McGhee, J.R.; Zhou, W.; Akagawa, K.; Fujiwara, T.; Thome, U.; Engelhardt, J.F.; Nelson, D.J.; Kirk, K.L.
    Syntaxin 1A is expressed in airway epithelial cells, where it modulates CFTR Cl(-) currents (2000), J. Clin. Invest., 105, 377-386.
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O + closed Cl- channel Homo sapiens CFTR function in epithelial cells is regulated by an interplay between syntaxin and Munc18 isoforms ADP + phosphate + open Cl- channel
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Organism

Organism UniProt Comment Textmining
Homo sapiens
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-
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Source Tissue

Source Tissue Comment Organism Textmining
epithelium
-
Homo sapiens
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + closed Cl- channel chloride channel Homo sapiens ADP + phosphate + open Cl- channel
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?
ATP + H2O + closed Cl- channel CFTR function in epithelial cells is regulated by an interplay between syntaxin and Munc18 isoforms Homo sapiens ADP + phosphate + open Cl- channel
-
?