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Literature summary for 5.6.1.5 extracted from
- Structural basis for dynamic regulation of the human 26S proteasome (2016), Proc. Natl. Acad. Sci. USA, 113, 12991-12996 .
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + H2O + polypeptide | Homo sapiens | - |
ADP + phosphate + unfolded polypeptide | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| NeutrAvidin agarose resin column chromatography, and Superose 6 gel filtration | Homo sapiens |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| HEK-293 cell | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + H2O + polypeptide | - |
Homo sapiens | ADP + phosphate + unfolded polypeptide | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| heterohexamer | - |
Homo sapiens |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| AAA-ATPase | - |
Homo sapiens |
| proteasome holoenzyme | - |
Homo sapiens |
| Rpt1 | subunit | Homo sapiens |
| Rpt2 | subunit | Homo sapiens |
| Rpt3 | subunit | Homo sapiens |
| Rpt4 | subunit | Homo sapiens |
| Rpt5 | subunit | Homo sapiens |
| Rpt6 | subunit | Homo sapiens |
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Release 2023.1 (January 2023)
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