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Literature summary for 5.6.1.5 extracted from

  • Kim, Y.; Snoberger, A.; Schupp, J.; Smith, D.
    ATP binding to neighbouring subunits and intersubunit allosteric coupling underlie proteasomal ATPase function (2015), Nat. Commun., 6, 8520 .
    View publication on PubMedView publication on EuropePMC

Protein Variants

Protein Variants Comment Organism
E271Q Walker B mutant Bos taurus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O + polypeptide Bos taurus
-
ADP + phosphate + unfolded polypeptide
-
?

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + polypeptide
-
Bos taurus ADP + phosphate + unfolded polypeptide
-
?
ATP + H2O + polypeptide GFPssrA
-
Bos taurus ADP + phosphate + unfolded polypeptide GFPssrA
-
?

Subunits

Subunits Comment Organism
hexamer
-
Bos taurus

Synonyms

Synonyms Comment Organism
proteasomal ATPase
-
Bos taurus
Rpt
-
Bos taurus
Rpt1 subunit Bos taurus
Rpt2 subunit Bos taurus
Rpt3 subunit Bos taurus
Rpt4 subunit Bos taurus
Rpt5 subunit Bos taurus
Rpt6 subunit Bos taurus

General Information

General Information Comment Organism
metabolism the enzyme complex binds and regulates the eukaroytic 26S proteasome Bos taurus