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Literature summary for 5.6.1.5 extracted from

  • Loew, P.; Bussell, K.; Dawson, S.P.; Billett, M.A.; Mayer, R.J.; Reynolds, S.E.
    Expression of a 26S proteasome ATPase subunit, MS73, in muscles that undergo developmentally programmed cell death, and its control by ecdysteroid hormones in the insect Manduca sexta (1997), FEBS Lett., 400, 345-349.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
cDNA clone encoding MS73 Manduca sexta

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
47000
-
SDS-PAGE Manduca sexta

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O + polypeptide Saccharomyces cerevisiae
-
ADP + phosphate + unfolded polypeptide
-
?
ATP + H2O + polypeptide Manduca sexta
-
ADP + phosphate + unfolded polypeptide
-
?

Organism

Organism UniProt Comment Textmining
Manduca sexta
-
tobacco hornworm moth
-
Saccharomyces cerevisiae
-
-
-

Reaction

Reaction Comment Organism Reaction ID
ATP + H2O + polypeptide = ADP + phosphate + unfolded polypeptide belongs to the AAA-type superfamily and, like EC 3.6.4.5, minus-end-directed kinesin ATPase, is involved in channel gating and polypeptide unfolding before proteolysis in the proteasome. Six ATPase subunits are present in the regulatory particle (RP) of 26S proteasome Saccharomyces cerevisiae
ATP + H2O + polypeptide = ADP + phosphate + unfolded polypeptide belongs to the AAA-type superfamily and, like EC 3.6.4.5, minus-end-directed kinesin ATPase, is involved in channel gating and polypeptide unfolding before proteolysis in the proteasome. Six ATPase subunits are present in the regulatory particle (RP) of 26S proteasome Manduca sexta

Source Tissue

Source Tissue Comment Organism Textmining
muscle
-
Manduca sexta
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + polypeptide
-
Saccharomyces cerevisiae ADP + phosphate + unfolded polypeptide
-
?
ATP + H2O + polypeptide
-
Manduca sexta ADP + phosphate + unfolded polypeptide
-
?

Synonyms

Synonyms Comment Organism
26S proteasome
-
Saccharomyces cerevisiae
26S proteasome
-
Manduca sexta
MS73 26S proteasome subunit Manduca sexta
YTA2
-
Saccharomyces cerevisiae