Literature summary for 5.6.1.4 extracted from

Hirose, K.; Akimaru, E.; Akiba, T.; Endow, S.A.; Amos, L.A.
Large conformational changes in a kinesin motor catalyzed by interaction with microtubules (2006), Mol. Cell, 23, 913-923.

Cloned(Commentary)

Cloned (Comment)	Organism
expression in Escherichia coli	Saccharomyces cerevisiae

Crystallization (Commentary)

Crystallization (Comment)	Organism
structure of microtubules decorated with Kar3 in the nucleotide-free state, as well as with ADP and 5'-adenylyl-beta,gamma-imidotriphosphate. The empty motor shows large structural changes, including melting of the switch II helix alpha4, closure of nucleotide-binding pocket, and changes in the central beta sheet. Structural changes in switch II control interactions of the Kar3 head with its neck and are transmitted via changes in the central beta sheet of the motor	Saccharomyces cerevisiae

Crystallization (Comment)

Organism

structure of microtubules decorated with Kar3 in the nucleotide-free state, as well as with ADP and 5'-adenylyl-beta,gamma-imidotriphosphate. The empty motor shows large structural changes, including melting of the switch II helix alpha4, closure of nucleotide-binding pocket, and changes in the central beta sheet. Structural changes in switch II control interactions of the Kar3 head with its neck and are transmitted via changes in the central beta sheet of the motor

Saccharomyces cerevisiae

Organism

Organism	UniProt	Comment	Textmining
Saccharomyces cerevisiae	-	isoform Kar3	-

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Release 2023.1 (January 2023)