BRENDA - Enzyme Database
show all sequences of 5.6.1.4

Minus-end capture of preformed kinetochore fibers contributes to spindle morphogenesis

Khodjakov, A.; Copenagle, L.; Gordon, M.B.; Compton, D.A.; Kapoor, T.M.; J. Cell Biol. 160, 671-683 (2003)

Data extracted from this reference:

Inhibitors
Inhibitors
Commentary
Organism
Structure
monastrol
application results in kinetochore fibers oriented away fom, and not directly connected to, centrosomes and incorporated into the spindle by the sliding of their distal ends toward centrosomes
Chlorocebus aethiops
monastrol
application results in kinetochore fibers oriented away fom, and not directly connected to, centrosomes and incorporated into the spindle by the sliding of their distal ends toward centrosomes
Potorous tridactylus
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Chlorocebus aethiops
-
-
-
Potorous tridactylus
-
-
-
Source Tissue
Source Tissue
Commentary
Organism
Textmining
CV-1 cell
-
Chlorocebus aethiops
-
Pt-K2 cell
-
Potorous tridactylus
-
Inhibitors (protein specific)
Inhibitors
Commentary
Organism
Structure
monastrol
application results in kinetochore fibers oriented away fom, and not directly connected to, centrosomes and incorporated into the spindle by the sliding of their distal ends toward centrosomes
Chlorocebus aethiops
monastrol
application results in kinetochore fibers oriented away fom, and not directly connected to, centrosomes and incorporated into the spindle by the sliding of their distal ends toward centrosomes
Potorous tridactylus
Source Tissue (protein specific)
Source Tissue
Commentary
Organism
Textmining
CV-1 cell
-
Chlorocebus aethiops
-
Pt-K2 cell
-
Potorous tridactylus
-
Other publictions for EC 5.6.1.4
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
752054
Locke
Structural basis of human kin ...
Homo sapiens
Proc. Natl. Acad. Sci. USA
114
E9539-E9548
2017
-
-
-
-
-
-
1
-
-
-
-
1
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
1
1
-
-
-
752278
Yamagishi
Structural basis of backwards ...
Rattus norvegicus
Structure
24
1322-1334
2016
-
-
-
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
733397
Dietrich
Identification of the kinesin ...
Homo sapiens
Biochim. Biophys. Acta
1833
3013-3024
2013
-
-
1
-
1
-
-
-
2
1
-
2
-
3
-
-
-
-
-
3
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
1
-
-
-
-
-
2
1
-
2
-
-
-
-
-
3
-
-
2
-
-
-
-
-
-
-
-
-
-
4
4
-
-
-
719508
Szczesna
The C-terminus of kinesin-14 N ...
Drosophila melanogaster
FEBS Lett.
586
854-858
2012
1
-
1
-
2
-
-
4
1
1
-
1
-
1
-
-
1
-
-
-
-
-
2
2
1
-
-
5
1
-
-
-
-
-
-
1
-
1
-
-
2
-
-
-
-
4
1
1
-
1
-
-
-
1
-
-
-
-
2
2
1
-
-
5
1
-
-
-
-
3
3
-
-
-
721005
Duan
Crystal structure of the Kar3- ...
Eremothecium gossypii
Proteins Struct. Funct. Bioinform.
80
1016-1027
2012
-
-
1
1
-
-
-
1
-
-
-
-
-
5
-
-
1
-
-
-
-
-
1
-
-
-
-
3
-
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
1
-
-
-
-
-
-
-
1
-
-
-
-
1
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
734196
Chen
The ATPase pathway that drives ...
Saccharomyces cerevisiae
J. Biol. Chem.
287
36673-36682
2012
-
-
1
-
-
-
-
1
2
1
2
1
-
2
-
-
-
-
-
-
-
-
1
-
1
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
1
2
1
2
1
-
-
-
-
-
-
-
-
1
-
1
-
-
-
1
-
-
-
-
4
4
-
-
-
719954
Chen
Kinesin Kar3Cik1 ATPase pathwa ...
Saccharomyces cerevisiae
J. Biol. Chem.
286
29261-29272
2011
-
-
1
-
-
-
-
1
3
-
-
-
-
2
-
-
1
-
-
-
-
-
1
1
-
-
-
1
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
1
3
-
-
-
-
-
-
1
-
-
-
-
1
1
-
-
-
1
-
-
-
-
-
-
-
-
-
-
713213
Hou
A coordinated molecular fishin ...
Saccharomyces cerevisiae
Phys. Biol.
7
036003
2010
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
1
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
1
1
-
-
-
719190
Heuston
A kinesin motor in a force-pro ...
Drosophila melanogaster
BMC Struct. Biol.
10
19
2010
-
-
1
1
1
-
-
-
-
-
-
-
-
1
-
-
1
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
720088
Hentrich
Microtubule organization by th ...
Xenopus laevis
J. Cell Biol.
189
465-480
2010
-
-
1
-
-
-
-
-
-
-
-
-
-
2
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
1
1
-
-
-
700097
Cai
Kinesin-14 family proteins HSE ...
Homo sapiens, Xenopus laevis
Mol. Biol. Cell
20
1348-1359
2009
-
-
2
-
1
-
3
-
-
-
-
2
-
4
-
-
2
-
-
1
-
-
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
1
-
-
3
-
-
-
-
-
2
-
-
-
2
-
1
-
-
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
700350
Braun
The kinesin-14 Klp2 organizes ...
Schizosaccharomyces pombe
Nat. Cell Biol.
11
724-730
2009
1
-
1
-
-
-
-
-
-
-
1
2
-
2
-
-
1
-
-
-
-
-
3
1
-
-
-
-
-
-
-
-
-
1
-
1
-
1
-
-
-
-
-
-
-
-
-
-
1
2
-
-
-
1
-
-
-
-
3
1
-
-
-
-
-
-
-
1
-
-
-
-
-
-
712404
Kocik
Interactions between subunits ...
Drosophila melanogaster
J. Biol. Chem.
284
35735-35745
2009
-
-
1
-
5
-
-
-
-
-
-
-
-
1
-
-
1
-
-
-
-
-
1
2
1
-
-
9
1
-
-
-
-
-
-
-
-
1
-
-
5
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
1
2
1
-
-
9
1
-
-
-
-
1
1
-
-
-
698412
Friedman
Inhibition of rat testicular n ...
Rattus norvegicus
J. Agric. Food Chem.
56
6024-6030
2008
-
-
-
-
-
-
3
-
1
-
-
-
-
2
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
3
-
-
1
-
-
-
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
698861
Furuta
Diffusion and directed movemen ...
Schizosaccharomyces pombe
J. Biol. Chem.
283
36465-36473
2008
1
-
1
-
-
-
-
1
-
-
-
1
-
2
-
-
1
-
-
-
-
-
2
1
-
-
-
1
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
-
-
1
-
-
-
1
-
-
-
1
-
-
-
-
2
1
-
-
-
1
-
-
-
-
-
-
-
-
-
-
685072
Ito
Coiled coil in the stalk regio ...
Drosophila melanogaster
Biochemistry
45
3315-3324
2006
-
-
-
-
-
-
-
-
-
-
-
-
-
3
-
-
-
-
1
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
688934
Hirose
Large conformational changes i ...
Saccharomyces cerevisiae
Mol. Cell
23
913-923
2006
-
-
1
1
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
689146
Endres
A lever-arm rotation drives mo ...
Drosophila melanogaster
Nature
439
875-878
2006
-
-
-
1
2
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
667670
Robin
Essential kinesins: characteri ...
Caenorhabditis elegans
Biochemistry
44
6526-6536
2005
1
-
1
-
-
-
-
-
-
1
2
1
-
2
-
-
-
-
-
-
-
-
2
1
-
-
-
1
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
-
-
-
-
1
2
1
-
-
-
-
-
-
-
-
2
1
-
-
-
1
-
-
-
-
-
-
-
-
-
-
668333
Sproul
Cik1 targets the minus-end kin ...
Saccharomyces cerevisiae
Curr. Biol.
15
1420-1427
2005
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
668405
Chu
Kar3 interaction with Cik1 alt ...
Saccharomyces cerevisiae
EMBO J.
24
3214-3223
2005
1
-
1
-
-
-
-
-
-
-
1
1
-
3
-
-
1
-
-
-
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
-
-
-
-
-
1
1
-
-
-
1
-
-
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
669577
Goshima
Mechanisms for focusing mitoti ...
Drosophila melanogaster
J. Cell Biol.
171
229-240
2005
-
-
-
-
-
-
-
-
1
-
-
1
-
1
-
-
-
-
-
1
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
1
-
-
-
-
-
1
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
656259
Mackey
Mechanistic analysis of the Sa ...
Saccharomyces cerevisiae
J. Biol. Chem.
279
51354-51361
2004
-
-
-
-
-
-
-
2
-
-
-
-
-
1
-
-
-
1
-
-
-
-
1
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
657073
Preuss
A plant-specific kinesin binds ...
Gossypium hirsutum
Plant Physiol.
136
3945-3955
2004
-
-
1
-
-
-
-
-
1
-
2
1
-
4
-
-
-
-
-
-
-
-
2
1
-
-
-
-
-
-
-
-
-
1
-
-
-
1
-
-
-
-
-
-
-
-
1
-
2
1
-
-
-
-
-
-
-
-
2
1
-
-
-
-
-
-
-
1
-
-
-
-
-
-
655282
Maddox
The minus end-directed motor K ...
Schizosaccharomyces pombe
Curr. Biol.
13
1423-1428
2003
-
-
-
-
-
-
-
-
-
-
-
1
-
1
-
-
-
1
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
655338
Yun
Rotation of the stalk/neck and ...
Drosophila melanogaster
EMBO J.
22
5382-5389
2003
-
-
-
1
3
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
656342
Khodjakov
Minus-end capture of preformed ...
Chlorocebus aethiops, Potorous tridactylus
J. Cell Biol.
160
671-683
2003
-
-
-
-
-
-
2
-
-
-
-
-
-
2
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
655191
Marcus
Arabidopsis thaliana protein, ...
Arabidopsis thaliana
Cell Motil. Cytoskeleton
52
144-150
2002
-
-
1
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
655330
Wendt
Microscopic evidence for a min ...
Drosophila melanogaster
EMBO J.
21
5969-5978
2002
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
1
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
656339
Noda
KIFC3, a microtubule minus end ...
Mus musculus
J. Cell Biol.
155
77-88
2001
-
-
-
-
1
-
-
-
1
-
-
1
-
1
-
-
-
-
-
4
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
1
-
-
-
-
-
4
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
210575
Mackey
Moving a microtubule may requi ...
Drosophila melanogaster
Biochemistry
39
1346-1355
2000
-
-
1
1
-
-
-
1
-
-
-
1
-
1
-
-
1
-
-
1
-
-
1
2
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
1
-
-
-
1
-
-
-
1
-
1
-
-
1
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
210551
Lane
Microtubule-based endoplasmic ...
Xenopus laevis
Mol. Biol.
10
1909-1922
1999
-
-
-
-
-
-
-
-
1
-
1
1
-
1
-
-
-
1
-
2
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
1
1
-
-
-
-
-
2
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
210572
Matuliene
Function of a minus-end-direct ...
Cricetulus griseus, Drosophila melanogaster, Homo sapiens, Mus musculus, Saccharomyces cerevisiae
J. Cell Sci.
112
4041-4050
1999
-
-
-
-
-
-
-
-
2
-
-
5
-
5
-
-
-
5
-
-
-
-
5
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
5
-
-
-
-
-
-
-
-
5
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
210574
Kozielski
The crystal structure of the m ...
Drosophila melanogaster
Structure Fold. Des.
7
1407-1416
1999
-
-
-
1
-
-
-
-
-
-
-
1
-
1
-
-
-
1
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
210571
Sablin
Direction determination in the ...
Drosophila melanogaster, Rattus norvegicus
Nature
395
813-816
1998
-
-
1
2
-
-
-
-
-
-
-
2
-
2
-
-
-
2
-
1
-
-
2
1
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
2
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
1
-
-
2
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
210568
Blocker
Molecular requirements for bi- ...
Bos taurus, Gallus gallus, Mus musculus, Rattus norvegicus
J. Cell Biol.
137
113-129
1997
-
-
-
-
-
-
-
-
3
-
2
4
-
4
-
-
-
4
-
5
-
-
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
3
-
2
4
-
-
-
-
-
5
-
-
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
210569
Sharp
Expression of a minus-end-dire ...
Cricetulus griseus
J. Cell Sci.
110
2373-2380
1997
-
-
1
-
-
-
-
-
-
-
-
1
-
1
-
-
-
1
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
210570
Henningsen
Reversal in the direction of m ...
Neurospora crassa
Nature
389
93-96
1997
-
-
1
-
-
-
-
-
-
-
1
1
-
3
-
-
1
1
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
1
1
-
-
-
1
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
210548
Song
Binding sites on microtubules ...
Drosophila melanogaster, Drosophila sp. (in: Insecta), Saccharomyces cerevisiae, Xenopus laevis
Biochemistry
35
11203-11209
1996
-
-
1
-
-
-
1
-
1
-
2
4
-
4
-
-
-
3
-
-
-
-
4
2
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
1
-
2
4
-
-
-
-
-
-
-
-
4
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
210567
Crevel
Weak and strong states of kine ...
Drosophila melanogaster, Drosophila sp. (in: Insecta), Saccharomyces cerevisiae
J. Mol. Biol.
257
66-76
1996
-
-
-
-
-
-
-
-
-
-
-
3
-
3
-
-
-
2
-
-
-
-
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
210545
Endow
Determinants of motor polarity ...
Aspergillus sp., Cricetulus griseus, Drosophila sp. (in: Insecta), Homo sapiens, Saccharomyces sp., Schizosaccharomyces pombe
Biophys. J.
68
271S-274S
1995
-
-
-
-
-
-
-
-
-
-
-
-
-
6
-
-
-
-
-
-
-
-
6
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
6
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
210546
Kuriyama
Characterization of a minus en ...
Arabidopsis sp., Aspergillus sp., Cricetulus griseus, Drosophila melanogaster, Homo sapiens, Saccharomyces cerevisiae
J. Cell Biol.
129
1049-1059
1995
-
-
-
-
-
-
-
-
-
-
-
6
-
7
-
-
-
6
-
-
-
-
6
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
6
-
-
-
-
-
-
-
-
6
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
210561
Lombillo
Minus-end-directed motion of k ...
Dictyostelium sp., Drosophila melanogaster, Homo sapiens, Tetrahymena sp.
Nature
373
161-164
1995
-
-
-
-
-
-
-
-
2
-
-
4
-
4
-
-
-
4
-
-
-
-
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
4
-
-
-
-
-
-
-
-
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
210562
Walker
Ncd and kinesin motor domains ...
Drosophila melanogaster, Drosophila sp. (in: Insecta)
Proc. Natl. Acad. Sci. USA
92
5960-5964
1995
-
-
-
-
-
-
-
-
1
-
-
2
-
2
-
-
1
1
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
2
-
-
-
1
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
210563
Shimizu
Comparison of the motile and e ...
Bos taurus, Doryteuthis pealeii, Drosophila melanogaster, Drosophila sp. (in: Insecta), Tetrahymena sp.
Biochemistry
34
1575-1582
1995
2
-
1
-
-
-
2
-
2
1
2
4
-
5
-
-
1
4
-
1
-
1
16
1
-
-
-
-
2
-
-
-
-
-
-
2
-
1
-
-
-
-
-
2
-
-
2
1
2
4
-
-
-
1
-
1
-
1
16
1
-
-
-
-
2
-
-
-
-
-
-
-
-
-
210565
Thrower
Mitotic HeLa cells contain a C ...
Dictyostelium sp., Homo sapiens, Xenopus laevis
EMBO J.
14
918-926
1995
-
-
-
-
-
-
3
-
2
-
2
3
-
3
-
-
1
3
-
1
-
-
5
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
3
-
-
2
-
2
3
-
-
-
1
-
1
-
-
5
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
210559
Endow
Yeast Kar3 is a minus-end micr ...
Arabidopsis sp., Drosophila melanogaster, Saccharomyces cerevisiae
EMBO J.
13
2708-2713
1994
-
-
1
-
-
-
-
-
-
-
-
3
-
3
-
-
1
3
-
-
-
-
3
-
-
-
-
1
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
3
-
-
-
1
-
-
-
-
3
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
210560
Middleton
KAR3-encoded kinesin is a minu ...
Drosophila melanogaster, Saccharomyces cerevisiae
Proc. Natl. Acad. Sci. USA
91
7212-7216
1994
-
-
1
-
-
-
-
-
1
-
2
2
-
3
-
-
1
2
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
2
2
-
-
-
1
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
210557
Walker
The Drosophila claret segregat ...
Drosophila melanogaster
Nature
347
780-782
1990
-
-
1
-
-
-
3
-
-
-
-
1
-
1
-
-
-
1
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
3
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
210558
McDonald
The kinesin-like ncd protein o ...
Drosophila melanogaster
Cell
63
1159-1165
1990
-
-
1
-
-
-
-
-
-
-
-
1
-
1
-
-
1
1
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
1
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-