Literature summary for 5.6.1.4 extracted from

Wendt, T.G.; Volkmann, N.; Skiniotis, G.; Goldie, K.N.; Muller, J.; Mandelkow, E.; Hoenger, A.
Microscopic evidence for a minus-end-directed power stroke in the kinesin motor ncd (2002), EMBO J., 21, 5969-5978.

Search for more literature for 5.6.1.4

Organism

Organism	UniProt	Comment	Textmining
Drosophila melanogaster	-	-	-

Reaction

Reaction	Comment	Organism	Reaction ID
ATP + H2O + a kinesin associated with a microtubule at position n = ADP + phosphate + a kinesin associated with a microtubule at position n-1 (toward the minus end)	mechanism, model of movement	Drosophila melanogaster	a

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
additional information	binding geometry between enzyme motor and microtubule which places the motor ahead of its cargo in the minus-end direction, after the uptake of ATP, the two heads rearrange their position relative to each other in a way that promotes a swing of the neck in the minus-end direction	Drosophila melanogaster	?	-	?

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Release 2023.1 (January 2023)