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Literature summary for 5.6.1.4 extracted from

  • Sharp, D.J.; Kuriyama, R.; Essner, R.; Baas, P.W.
    Expression of a minus-end-directed motor protein induces Sf9 cells to form axon-like processes with uniform microtubule polarity orientation (1997), J. Cell Sci., 110, 2373-2380.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
baculovirus constructs encoding the entire CHO2 molecule expressed in Sf9 cells Cricetulus griseus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O + a kinesin associated with a microtubule at position n Cricetulus griseus
-
ADP + phosphate + a kinesin associated with a microtubule at position n-1 (toward the minus end)
-
?

Organism

Organism UniProt Comment Textmining
Cricetulus griseus
-
chinese hamster
-

Reaction

Reaction Comment Organism Reaction ID
ATP + H2O + a kinesin associated with a microtubule at position n = ADP + phosphate + a kinesin associated with a microtubule at position n-1 (toward the minus end) structurally almost identical to EC3.6.4.3 (microtubule-severing ATPase) but the movement it catalyses is towards the minus end of microtubules Cricetulus griseus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + a kinesin associated with a microtubule at position n
-
Cricetulus griseus ADP + phosphate + a kinesin associated with a microtubule at position n-1 (toward the minus end)
-
?

Synonyms

Synonyms Comment Organism
CHO1/MKLP1
-
Cricetulus griseus
CHO2
-
Cricetulus griseus