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Literature summary for 5.6.1.4 extracted from

  • Walker, R.A.
    Ncd and kinesin motor domains interact with both alpha- and beta-tubulin (1995), Proc. Natl. Acad. Sci. USA, 92, 5960-5964.
    View publication on PubMedView publication on EuropePMC

Localization

Localization Comment Organism GeneOntology No. Textmining
microtubule ncd motor domain interacts with both alpha- and beta-tubulin Drosophila sp. (in: flies) 5874
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O + a kinesin associated with a microtubule at position n Drosophila melanogaster
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ADP + phosphate + a kinesin associated with a microtubule at position n-1 (toward the minus end)
-
?
ATP + H2O + a kinesin associated with a microtubule at position n Drosophila sp. (in: flies) ncd motor domain interacts with both alpha- and beta-tubulin ADP + phosphate + a kinesin associated with a microtubule at position n-1 (toward the minus end)
-
?

Organism

Organism UniProt Comment Textmining
Drosophila melanogaster
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-
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Drosophila sp. (in: flies)
-
-
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Purification (Commentary)

Purification (Comment) Organism
-
Drosophila melanogaster

Reaction

Reaction Comment Organism Reaction ID
ATP + H2O + a kinesin associated with a microtubule at position n = ADP + phosphate + a kinesin associated with a microtubule at position n-1 (toward the minus end) structurally almost identical to EC3.6.4.3 (microtubule-severing ATPase) but the movement it catalyses is towards the minus end of microtubules Drosophila melanogaster

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + a kinesin associated with a microtubule at position n
-
Drosophila melanogaster ADP + phosphate + a kinesin associated with a microtubule at position n-1 (toward the minus end)
-
?
ATP + H2O + a kinesin associated with a microtubule at position n
-
Drosophila sp. (in: flies) ADP + phosphate + a kinesin associated with a microtubule at position n-1 (toward the minus end)
-
?
ATP + H2O + a kinesin associated with a microtubule at position n ncd motor domain interacts with both alpha- and beta-tubulin Drosophila sp. (in: flies) ADP + phosphate + a kinesin associated with a microtubule at position n-1 (toward the minus end)
-
?

Synonyms

Synonyms Comment Organism
ncd
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Drosophila melanogaster
ncd
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Drosophila sp. (in: flies)