Cloned (Comment) | Organism |
---|---|
expressed in Escherichia coli BL21 cells | Xenopus laevis |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Xenopus laevis | full-length Eg5's motility comprises an unbiased, diffusive mode independent of ATP hydrolysis and a plus end-directed processive mode that requires ATP hydrolysis, Eg5 can switch from diffusive motility to directional motility upon binding to a second microtubule | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Xenopus laevis | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Xenopus laevis |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + H2O + a kinesin associated with a microtubule at position n | - |
Xenopus laevis | ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end) | - |
? | |
additional information | full-length Eg5's motility comprises an unbiased, diffusive mode independent of ATP hydrolysis and a plus end-directed processive mode that requires ATP hydrolysis, Eg5 can switch from diffusive motility to directional motility upon binding to a second microtubule | Xenopus laevis | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
tetramer | a homotetramer-specific diffusive mode keeps full-length Eg5 attached to a microtubule for longer times at near physiological conditions | Xenopus laevis |
Synonyms | Comment | Organism |
---|---|---|
Eg5 | - |
Xenopus laevis |
kinesin-5 | - |
Xenopus laevis |