Cloned (Comment) | Organism |
---|---|
overexpression of dominant negative forms of the KIF3A motor subunit and the KAp3 accessory subunit in HeLa cells | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + H2O + a kinesin associated with a microtubule at position n | Homo sapiens | kinesin-2 is required for the normal steady-state localization of late endosomes/lysosomes but not early ensosomes or recycling endosomes. Kinesin-2 contributes significantly to the plus-end-directed movement of late endosomes and lysosomes | ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end) | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + H2O + a kinesin associated with a microtubule at position n | - |
Homo sapiens | ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end) | - |
? | |
ATP + H2O + a kinesin associated with a microtubule at position n | kinesin-2 is required for the normal steady-state localization of late endosomes/lysosomes but not early ensosomes or recycling endosomes. Kinesin-2 contributes significantly to the plus-end-directed movement of late endosomes and lysosomes | Homo sapiens | ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end) | - |
? |
Synonyms | Comment | Organism |
---|---|---|
KIF3A | motor subunit | Homo sapiens |
kinesin-2 | - |
Homo sapiens |