Literature summary for 5.6.1.3 extracted from

Hoepfner, S.; Severin, F.; Cabezas, A.; Habermann, B.; Runge, A.; Gillooly, D.; Stenmark, H.; Zerial, M.
Modulation of receptor recycling and degradation by the endosomal kinesin KIF16B (2005), Cell, 121, 437-450.

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Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
endosome	kinesin KIF16B transports early endosomes to the plus end of microtubules	Homo sapiens	5768	-

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
ATP + H2O + a kinesin associated with a microtubule at position n	Homo sapiens	in regulating plus end motility, KIF16B governs the spatial distribution of early endosomes in vivo and the balance between receptor recycling and degradation	ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end)	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	Q96L93	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + H2O + a kinesin associated with a microtubule at position n	in regulating plus end motility, KIF16B governs the spatial distribution of early endosomes in vivo and the balance between receptor recycling and degradation	Homo sapiens	ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end)	-	?
ATP + H2O + a kinesin associated with a microtubule at position n	KIF16B is a plus end-directed motor	Homo sapiens	ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end)	-	?

Synonyms

Synonyms	Comment	Organism
kinesin KIF16B	-	Homo sapiens
kinesin-like motor protein C20orf23	-	Homo sapiens

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Release 2023.1 (January 2023)