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Literature summary for 5.6.1.3 extracted from

  • Kirchner, J.; Woehlke, G.; Schliwa, M.
    Universal and unique features of kinesin motors: insights from a comparison of fungal and animal conventional kinesins (1999), Biol. Chem., 380, 915-921.
    View publication on PubMed

Crystallization (Commentary)

Crystallization (Comment) Organism
-
Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
axon
-
Drosophila sp. (in: flies) 30424
-
axon
-
Doryteuthis pealeii 30424
-
endoplasmic reticulum
-
Mus musculus 5783
-
endoplasmic reticulum
-
Homo sapiens 5783
-
Golgi apparatus
-
Homo sapiens 5794
-
Golgi apparatus
-
Doryteuthis pealeii 5794
-
lysosome
-
Doryteuthis pealeii 5764
-
mitochondrion
-
Doryteuthis pealeii 5739
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O + a kinesin associated with a microtubule at position n Drosophila melanogaster
-
ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
ATP + H2O + a kinesin associated with a microtubule at position n Drosophila sp. (in: flies)
-
ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
ATP + H2O + a kinesin associated with a microtubule at position n Mus musculus
-
ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
ATP + H2O + a kinesin associated with a microtubule at position n Homo sapiens
-
ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
ATP + H2O + a kinesin associated with a microtubule at position n Rattus norvegicus
-
ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
ATP + H2O + a kinesin associated with a microtubule at position n Bos taurus
-
ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
ATP + H2O + a kinesin associated with a microtubule at position n Neurospora crassa
-
ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
ATP + H2O + a kinesin associated with a microtubule at position n Caenorhabditis elegans
-
ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
ATP + H2O + a kinesin associated with a microtubule at position n Ustilago maydis
-
ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
ATP + H2O + a kinesin associated with a microtubule at position n Fusarium solani
-
ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
ATP + H2O + a kinesin associated with a microtubule at position n Strongylocentrotus purpuratus
-
ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
ATP + H2O + a kinesin associated with a microtubule at position n Doryteuthis pealeii
-
ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
GTP + H2O + a kinesin associated with a microtubule at position n Drosophila melanogaster
-
GDP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
GTP + H2O + a kinesin associated with a microtubule at position n Drosophila sp. (in: flies)
-
GDP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
GTP + H2O + a kinesin associated with a microtubule at position n Mus musculus
-
GDP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
GTP + H2O + a kinesin associated with a microtubule at position n Homo sapiens
-
GDP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
GTP + H2O + a kinesin associated with a microtubule at position n Rattus norvegicus
-
GDP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
GTP + H2O + a kinesin associated with a microtubule at position n Bos taurus
-
GDP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
GTP + H2O + a kinesin associated with a microtubule at position n Neurospora crassa
-
GDP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
GTP + H2O + a kinesin associated with a microtubule at position n Caenorhabditis elegans
-
GDP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
GTP + H2O + a kinesin associated with a microtubule at position n Ustilago maydis
-
GDP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
GTP + H2O + a kinesin associated with a microtubule at position n Fusarium solani
-
GDP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
GTP + H2O + a kinesin associated with a microtubule at position n Strongylocentrotus purpuratus
-
GDP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
GTP + H2O + a kinesin associated with a microtubule at position n Doryteuthis pealeii
-
GDP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-
Caenorhabditis elegans
-
-
-
Doryteuthis pealeii
-
-
-
Drosophila melanogaster
-
-
-
Drosophila sp. (in: flies)
-
-
-
Fusarium solani
-
-
-
Homo sapiens
-
-
-
Mus musculus
-
-
-
Neurospora crassa
-
-
-
Rattus norvegicus
-
-
-
Strongylocentrotus purpuratus
-
sea urchin
-
Ustilago maydis
-
-
-

Reaction

Reaction Comment Organism Reaction ID
ATP + H2O + a kinesin associated with a microtubule at position n = ADP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end) microtubular motor protein, involved in organelle movement, in mitosis and meiosis. In contrast to dynein, it moves along microtubules towards the plus end. Composed of two heavy (a) chains (110kDa) and two more light (b) chains (65-75 kDa). Also hydrolyzes GTP. Drosophila melanogaster
ATP + H2O + a kinesin associated with a microtubule at position n = ADP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end) microtubular motor protein, involved in organelle movement, in mitosis and meiosis. In contrast to dynein, it moves along microtubules towards the plus end. Composed of two heavy (a) chains (110kDa) and two more light (b) chains (65-75 kDa). Also hydrolyzes GTP. Drosophila sp. (in: flies)
ATP + H2O + a kinesin associated with a microtubule at position n = ADP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end) microtubular motor protein, involved in organelle movement, in mitosis and meiosis. In contrast to dynein, it moves along microtubules towards the plus end. Composed of two heavy (a) chains (110kDa) and two more light (b) chains (65-75 kDa). Also hydrolyzes GTP. Mus musculus
ATP + H2O + a kinesin associated with a microtubule at position n = ADP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end) microtubular motor protein, involved in organelle movement, in mitosis and meiosis. In contrast to dynein, it moves along microtubules towards the plus end. Composed of two heavy (a) chains (110kDa) and two more light (b) chains (65-75 kDa). Also hydrolyzes GTP. Homo sapiens
ATP + H2O + a kinesin associated with a microtubule at position n = ADP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end) microtubular motor protein, involved in organelle movement, in mitosis and meiosis. In contrast to dynein, it moves along microtubules towards the plus end. Composed of two heavy (a) chains (110kDa) and two more light (b) chains (65-75 kDa). Also hydrolyzes GTP. Rattus norvegicus
ATP + H2O + a kinesin associated with a microtubule at position n = ADP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end) microtubular motor protein, involved in organelle movement, in mitosis and meiosis. In contrast to dynein, it moves along microtubules towards the plus end. Composed of two heavy (a) chains (110kDa) and two more light (b) chains (65-75 kDa). Also hydrolyzes GTP. Bos taurus
ATP + H2O + a kinesin associated with a microtubule at position n = ADP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end) microtubular motor protein, involved in organelle movement, in mitosis and meiosis. In contrast to dynein, it moves along microtubules towards the plus end. Composed of two heavy (a) chains (110kDa) and two more light (b) chains (65-75 kDa). Also hydrolyzes GTP. Neurospora crassa
ATP + H2O + a kinesin associated with a microtubule at position n = ADP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end) microtubular motor protein, involved in organelle movement, in mitosis and meiosis. In contrast to dynein, it moves along microtubules towards the plus end. Composed of two heavy (a) chains (110kDa) and two more light (b) chains (65-75 kDa). Also hydrolyzes GTP. Caenorhabditis elegans
ATP + H2O + a kinesin associated with a microtubule at position n = ADP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end) microtubular motor protein, involved in organelle movement, in mitosis and meiosis. In contrast to dynein, it moves along microtubules towards the plus end. Composed of two heavy (a) chains (110kDa) and two more light (b) chains (65-75 kDa). Also hydrolyzes GTP. Ustilago maydis
ATP + H2O + a kinesin associated with a microtubule at position n = ADP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end) microtubular motor protein, involved in organelle movement, in mitosis and meiosis. In contrast to dynein, it moves along microtubules towards the plus end. Composed of two heavy (a) chains (110kDa) and two more light (b) chains (65-75 kDa). Also hydrolyzes GTP. Fusarium solani
ATP + H2O + a kinesin associated with a microtubule at position n = ADP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end) microtubular motor protein, involved in organelle movement, in mitosis and meiosis. In contrast to dynein, it moves along microtubules towards the plus end. Composed of two heavy (a) chains (110kDa) and two more light (b) chains (65-75 kDa). Also hydrolyzes GTP. Strongylocentrotus purpuratus
ATP + H2O + a kinesin associated with a microtubule at position n = ADP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end) microtubular motor protein, involved in organelle movement, in mitosis and meiosis. In contrast to dynein, it moves along microtubules towards the plus end. Composed of two heavy (a) chains (110kDa) and two more light (b) chains (65-75 kDa). Also hydrolyzes GTP. Doryteuthis pealeii

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
Mus musculus
-
brain
-
Bos taurus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + a kinesin associated with a microtubule at position n
-
Drosophila melanogaster ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
ATP + H2O + a kinesin associated with a microtubule at position n
-
Drosophila sp. (in: flies) ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
ATP + H2O + a kinesin associated with a microtubule at position n
-
Mus musculus ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
ATP + H2O + a kinesin associated with a microtubule at position n
-
Homo sapiens ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
ATP + H2O + a kinesin associated with a microtubule at position n
-
Rattus norvegicus ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
ATP + H2O + a kinesin associated with a microtubule at position n
-
Bos taurus ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
ATP + H2O + a kinesin associated with a microtubule at position n
-
Neurospora crassa ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
ATP + H2O + a kinesin associated with a microtubule at position n
-
Caenorhabditis elegans ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
ATP + H2O + a kinesin associated with a microtubule at position n
-
Ustilago maydis ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
ATP + H2O + a kinesin associated with a microtubule at position n
-
Fusarium solani ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
ATP + H2O + a kinesin associated with a microtubule at position n
-
Strongylocentrotus purpuratus ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
ATP + H2O + a kinesin associated with a microtubule at position n
-
Doryteuthis pealeii ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
GTP + H2O + a kinesin associated with a microtubule at position n
-
Drosophila melanogaster GDP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
GTP + H2O + a kinesin associated with a microtubule at position n
-
Drosophila sp. (in: flies) GDP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
GTP + H2O + a kinesin associated with a microtubule at position n
-
Mus musculus GDP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
GTP + H2O + a kinesin associated with a microtubule at position n
-
Homo sapiens GDP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
GTP + H2O + a kinesin associated with a microtubule at position n
-
Rattus norvegicus GDP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
GTP + H2O + a kinesin associated with a microtubule at position n
-
Bos taurus GDP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
GTP + H2O + a kinesin associated with a microtubule at position n
-
Neurospora crassa GDP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
GTP + H2O + a kinesin associated with a microtubule at position n
-
Caenorhabditis elegans GDP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
GTP + H2O + a kinesin associated with a microtubule at position n
-
Ustilago maydis GDP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
GTP + H2O + a kinesin associated with a microtubule at position n
-
Fusarium solani GDP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
GTP + H2O + a kinesin associated with a microtubule at position n
-
Strongylocentrotus purpuratus GDP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
GTP + H2O + a kinesin associated with a microtubule at position n
-
Doryteuthis pealeii GDP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?

Subunits

Subunits Comment Organism
dimer
-
Drosophila sp. (in: flies)
dimer
-
Mus musculus
dimer
-
Rattus norvegicus
dimer SDS-PAGE Homo sapiens

Synonyms

Synonyms Comment Organism
KIF5A
-
Mus musculus
KIF5A
-
Homo sapiens
KIF5C
-
Mus musculus
KIF5C
-
Homo sapiens