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Literature summary for 5.6.1.2 extracted from

  • Toba, S.; Watanabe, T.M.; Yamaguchi-Okimoto, L.; Toyoshima, Y.Y.; Higuchi, H.
    Overlapping hand-over-hand mechanism of single molecular motility of cytoplasmic dynein (2006), Proc. Natl. Acad. Sci. USA, 103, 5741-5745.
    View publication on PubMedView publication on EuropePMC
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Organism

Organism UniProt Comment Textmining
Sus scrofa
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Source Tissue

Source Tissue Comment Organism Textmining
brain
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 Sus scrofa
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information measurement of mechanical properties of single dynein molecules. the velocity of dynein movement is around 800 nm/s, the maximum force is 7-8 pN and independent of the ATP concentration. Dynein exhibits forward and backward steps of 8 nm, independent of load. The large dynein heads may take 16 nm steps by using an overlapping hand-over-hand mechanism Sus scrofa ?
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