Literature summary for 5.6.1.2 extracted from

FitzHarris, G.; Marangos, P.; Carroll, J.
Changes in endoplasmic reticulum structure during mouse oocyte maturation are controlled by the cytoskeleton and cytoplasmic dynein (2007), Dev. Biol., 305, 133-144.

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Application

Application	Comment	Organism
medicine	redistribution of endoplasmic reticulum during oocyte maturation is dynein-driven and cell cycle-dependent. Role for dynein in the cytoplasmic changes that prepare the oocyte for fertilization	Mus musculus

Inhibitors

Inhibitors	Comment	Organism	Structure
antibody 70.1	antibody raised against the intermediate chain of dynein, exerts a functional inhibitory effect upon dynein function by preventing its association with the accessory complex dynactin. Treatment with 70.1 prevents formation of the prominent endoplasmic reticulum ring characteristic of metaphase I oocytes	Mus musculus
vanadate	vanadate treatment prevents formation of the prominent endoplasmic reticulum ring characteristic of metaphase I oocytes	Mus musculus

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
endoplasmic reticulum	redistribution of endoplasmic reticulum during oocyte maturation is dynein-driven and cell cycle-dependent	Mus musculus	5783	-

Organism

Organism	UniProt	Comment	Textmining
Mus musculus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
oocyte	redistribution of endoplasmic reticulum during oocyte maturation is dynein-driven and cell cycle-dependent. Role for dynein in the cytoplasmic changes that prepare the oocyte for fertilization	Mus musculus	-

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Release 2023.1 (January 2023)