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Literature summary for 5.6.1.2 extracted from

  • Adhiambo, C.; Forney, J.D.; Asai, D.J.; LeBowitz, J.H.
    The two cytoplasmic dynein-2 isoforms in Leishmania mexicana perform separate functions (2005), Mol. Biochem. Parasitol., 143, 216-225.
    View publication on PubMed
Search for more literature for 5.6.1.2

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm
-
 Trypanosoma brucei 5737
-
cytoplasm
-
 Leishmania infantum 5737
-
cytoplasm
-
 Leishmania mexicana 5737
-
cytoplasm
-
 Leishmania major 5737
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O + a dynein associated with a microtubule at position n Trypanosoma brucei
-
 ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
 ?
ATP + H2O + a dynein associated with a microtubule at position n Leishmania infantum
-
 ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
 ?
ATP + H2O + a dynein associated with a microtubule at position n Leishmania major
-
 ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
 ?
ATP + H2O + a dynein associated with a microtubule at position n Leishmania mexicana cytoplasmic dynein heavy chain 2.2 is required for flagellar assembly and also participates in maintenance of promastigote cell shape. LmxDHC2.2 is not an essential gene ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
 ?
ATP + H2O + a dynein associated with a microtubule at position n Leishmania mexicana Lmxdhc2.1 that encodes cytoplasmic dynein heavy chain 2.1 is an essentail gene in Leishmania ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
 ?

Organism

Organism UniProt Comment Textmining
Leishmania infantum
-
 organism contains two dynein-2 isoforms
-
Leishmania major Q4QBN6 cytoplasmic dynein, heavy chain 1; organism contains two dynein-2 isoforms
-
Leishmania mexicana Q4KXA6 cytoplasmic dynein heavy chain 2.1
-
Leishmania mexicana Q4KXA7 cytoplasmic dynein heavy chain 2.2
-
Trypanosoma brucei
-
 organism contains two dynein-2 isoforms
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + a dynein associated with a microtubule at position n
-
 Trypanosoma brucei ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
 ?
ATP + H2O + a dynein associated with a microtubule at position n
-
 Leishmania infantum ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
 ?
ATP + H2O + a dynein associated with a microtubule at position n
-
 Leishmania major ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
 ?
ATP + H2O + a dynein associated with a microtubule at position n cytoplasmic dynein heavy chain 2.2 is required for flagellar assembly and also participates in maintenance of promastigote cell shape. LmxDHC2.2 is not an essential gene Leishmania mexicana ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
 ?
ATP + H2O + a dynein associated with a microtubule at position n Lmxdhc2.1 that encodes cytoplasmic dynein heavy chain 2.1 is an essentail gene in Leishmania Leishmania mexicana ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
 ?

Synonyms

Synonyms Comment Organism
cytoplasmic dynein heavy chain 2.1
-
 Leishmania mexicana
cytoplasmic dynein heavy chain 2.2
-
 Leishmania mexicana
dynein-2
-
 Trypanosoma brucei
dynein-2
-
 Leishmania infantum
dynein-2
-
 Leishmania mexicana
dynein-2
-
 Leishmania major