Literature summary for 5.6.1.1 extracted from

Karabay, A.; Yu, W.; Solowska, J.M.; Baird, D.H.; Baas, P.W.
Axonal growth is sensitive to the levels of katanin, a protein that severs microtubules (2004), J. Neurosci., 24, 5778-5788.

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Protein Variants

Protein Variants	Comment	Organism
additional information	expression of a dominant-negative enzyme construct inhibits microtubule severing and is deleterious to axonal growth. Overexpression of wild-type enzyme results in excess microtubule severing and is also deleterious to axonal growth in some of the neurons	Rattus norvegicus

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
60000	-	x * 60000, SDS-PAGE	Rattus norvegicus

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	Q6E0V2	P60 katanin, enzyme expression changes during development of the nervous system and correlates with axonal growth	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
brain	-	Rattus norvegicus	-

Subunits

Subunits	Comment	Organism
?	x * 60000, SDS-PAGE	Rattus norvegicus

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Release 2023.1 (January 2023)