Cloned (Comment) | Organism |
---|---|
human katanin cloned and expressed in Escherichia coli | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
ADP | - |
Chlamydomonas reinhardtii | |
ADP | - |
Strongylocentrotus purpuratus | |
ATPgammaS | - |
Chlamydomonas reinhardtii | |
ATPgammaS | - |
Strongylocentrotus purpuratus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
centrosome | - |
Homo sapiens | 5813 | - |
centrosome | - |
Xenopus laevis | 5813 | - |
centrosome | - |
Strongylocentrotus purpuratus | 5813 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | - |
Chlamydomonas reinhardtii |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
55000 | - |
Western analysis using a polyclonal antibody against the 60 kDa subunit of human katanin | Chlamydomonas reinhardtii |
60000 | - |
- |
Homo sapiens |
60000 | - |
- |
Strongylocentrotus purpuratus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + H2O | Chlamydomonas reinhardtii | - |
ADP + phosphate | - |
? | |
ATP + H2O | Homo sapiens | - |
ADP + phosphate | - |
? | |
ATP + H2O | Xenopus laevis | - |
ADP + phosphate | - |
? | |
ATP + H2O | Strongylocentrotus purpuratus | - |
ADP + phosphate | - |
? | |
GTP + H2O | Chlamydomonas reinhardtii | - |
GDP + phosphate | - |
? | |
GTP + H2O | Homo sapiens | - |
GDP + phosphate | - |
? | |
GTP + H2O | Xenopus laevis | - |
GDP + phosphate | - |
? | |
GTP + H2O | Strongylocentrotus purpuratus | - |
GDP + phosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Chlamydomonas reinhardtii | - |
strains 137c, cc620 and cc621 | - |
Homo sapiens | - |
human | - |
Strongylocentrotus purpuratus | - |
sea urchin | - |
Xenopus laevis | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Chlamydomonas reinhardtii |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
n ATP + n H2O + a microtubule = n ADP + n phosphate + (n+1) alpha/beta tubulin heterodimers | another member of the AAA-ATPase family, active in splitting microtubules into tubulin dimers in the centrosome | Chlamydomonas reinhardtii | |
n ATP + n H2O + a microtubule = n ADP + n phosphate + (n+1) alpha/beta tubulin heterodimers | another member of the AAA-ATPase family, active in splitting microtubules into tubulin dimers in the centrosome | Homo sapiens | |
n ATP + n H2O + a microtubule = n ADP + n phosphate + (n+1) alpha/beta tubulin heterodimers | another member of the AAA-ATPase family, active in splitting microtubules into tubulin dimers in the centrosome | Xenopus laevis | |
n ATP + n H2O + a microtubule = n ADP + n phosphate + (n+1) alpha/beta tubulin heterodimers | another member of the AAA-ATPase family, active in splitting microtubules into tubulin dimers in the centrosome | Strongylocentrotus purpuratus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
oocyte | - |
Xenopus laevis | - |
oocyte | - |
Strongylocentrotus purpuratus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + H2O | - |
Chlamydomonas reinhardtii | ADP + phosphate | - |
? | |
ATP + H2O | - |
Homo sapiens | ADP + phosphate | - |
? | |
ATP + H2O | - |
Xenopus laevis | ADP + phosphate | - |
? | |
ATP + H2O | - |
Strongylocentrotus purpuratus | ADP + phosphate | - |
? | |
GTP + H2O | - |
Chlamydomonas reinhardtii | GDP + phosphate | - |
? | |
GTP + H2O | - |
Homo sapiens | GDP + phosphate | - |
? | |
GTP + H2O | - |
Xenopus laevis | GDP + phosphate | - |
? | |
GTP + H2O | - |
Strongylocentrotus purpuratus | GDP + phosphate | - |
? |