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Literature summary for 5.5.1.4 extracted from
- Anomeric and other substrate specificity studies with myo-inositol-1-P synthase (1985), J. Biol. Chem., 260, 11083-11090.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 2-Deoxy-2-fluoroglucose 6-phosphate | competitive | Bos taurus |  |
| 2-deoxy-D-glucose 6-phosphate | competitive | Bos taurus | |
| D-Allose 6-phosphate | - |
Bos taurus | |
| D-glucose 6-phosphate | the beta-anomer is preferred as substrate, the alpha-anomer is an inhibitor | Bos taurus | |
| D-mannose 6-phosphate | competitive | Bos taurus | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bos taurus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| testis | - |
Bos taurus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 2-deoxy-D-glucose 6-phosphate | - |
Bos taurus | 5-deoxy-L-myo-inositol 1-phosphate | - |
? | |
| D-2-Deoxy-2-fluoroglucose 6-phosphate | - |
Bos taurus | 5-Deoxy-5-fluoro-myo-inositol 1-phosphate | - |
? | |
| D-Glucose 6-phosphate | at least 5-fold preference for the beta-anomer | Bos taurus | L-myo-Inositol 1-phosphate | - |
? | |
| D-Mannose 6-phosphate | - |
Bos taurus | myo-Inositol 1-phosphate | - |
? | |
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Release 2023.1 (January 2023)
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