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Literature summary for 5.4.99.B22 extracted from

  • Tillault, A.S.; Schultz, S.K.; Wieden, H.J.; Kothe, U.
    Molecular determinants for 23S rRNA recognition and modification by the E. coli pseudouridine synthase RluE (2018), J. Mol. Biol., 430, 1284-1294 .
    View publication on PubMed
Search for more literature for 5.4.99.B22

Cloned(Commentary)

Cloned (Comment) Organism
-
 Escherichia coli

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
23S rRNA uridine2457 Escherichia coli RluE forms a highly conserved pseudouridine during ribosome biogenesis 23S rRNA pseudouridine2457
-
 ?
23S rRNA uridine2457 Escherichia coli K12 RluE forms a highly conserved pseudouridine during ribosome biogenesis 23S rRNA pseudouridine2457
-
 ?

Organism

Organism UniProt Comment Textmining
Escherichia coli P75966
-
-
Escherichia coli K12 P75966
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Escherichia coli

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
23S rRNA uridine2457 RluE forms a highly conserved pseudouridine during ribosome biogenesis Escherichia coli 23S rRNA pseudouridine2457
-
 ?
23S rRNA uridine2457 RluE recognizes a large part of 23S rRNA comprising both H89 and the single-stranded flanking regions which explains the high substrate specificity of RluE Escherichia coli 23S rRNA pseudouridine2457
-
 ?
23S rRNA uridine2457 RluE forms a highly conserved pseudouridine during ribosome biogenesis Escherichia coli K12 23S rRNA pseudouridine2457
-
 ?

Synonyms

Synonyms Comment Organism
RluE
-
 Escherichia coli
YmfC
-
 Escherichia coli

General Information

General Information Comment Organism
metabolism RluE is a faster pseudouridine synthase than other enzymes which likely enables it to act in the early stages of ribosome form Escherichia coli