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Literature summary for 5.4.99.9 extracted from

  • Caravano, A.; Sinay, P.; Vincent, S.P.
    1,4-Anhydrogalactopyranose is not an intermediate of the mutase catalyzed UDP-galactopyranose/furanose interconversion (2006), Bioorg. Med. Chem. Lett., 16, 1123-1125.
    View publication on PubMed
Search for more literature for 5.4.99.9

Inhibitors

Inhibitors Comment Organism Structure
additional information fluorinated substrate analogues under non-reducing conditions Mycobacterium tuberculosis
UDP
-
 Mycobacterium tuberculosis

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.02
-
 UDP-galactofuranose under reducing conditions Mycobacterium tuberculosis
0.19
-
 UDP-galactofuranose under non-reducing (native) conditions Mycobacterium tuberculosis

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
UDP-galactopyranose Mycobacterium tuberculosis essential step of mycobacterial cell wall biosynthesis UDP-galactofuranose
-
 r

Organism

Organism UniProt Comment Textmining
Mycobacterium tuberculosis
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information 1,4-anhydrogalactopyranose does not react with UGM and UDP to form UDP-galactopyranose or UDP-galactofuranose Mycobacterium tuberculosis ?
-
 ?
UDP-galactopyranose
-
 Mycobacterium tuberculosis UDP-galactofuranose
-
 r
UDP-galactopyranose essential step of mycobacterial cell wall biosynthesis Mycobacterium tuberculosis UDP-galactofuranose
-
 r

Synonyms

Synonyms Comment Organism
UDP-galactopyranose mutase
-
 Mycobacterium tuberculosis
UGM
-
 Mycobacterium tuberculosis

Cofactor

Cofactor Comment Organism Structure
FAD
-
 Mycobacterium tuberculosis

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.2
-
 UDP
-
 Mycobacterium tuberculosis