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Literature summary for 5.4.99.9 extracted from

  • Sanders, D.A.; Staines, A.G.; McMahon, S.A.; McNeil, M.R.; Whitfield, C.; Naismith, J.H.
    UDP-galactopyranose mutase has a novel structure and mechanism (2001), Nat. Struct. Biol., 8, 858-863.
    View publication on PubMed
Search for more literature for 5.4.99.9

Cloned(Commentary)

Cloned (Comment) Organism
overexpression in Escherichia coli Klebsiella pneumoniae
overexpression in Escherichia coli Escherichia coli

Crystallization (Commentary)

Crystallization (Comment) Organism
FAD is located in a cleft lined with conserved residues Escherichia coli

Protein Variants

Protein Variants Comment Organism
W156A lower activity than wild-type enzyme Klebsiella pneumoniae
W156Y lower activity than wild-type enzyme Klebsiella pneumoniae
Y151F lower activity than wild-type enzyme Klebsiella pneumoniae
Y181F lower activity than wild-type enzyme Klebsiella pneumoniae
Y311F lower activity than wild-type enzyme Klebsiella pneumoniae
Y346F lower activity than wild-type enzyme Klebsiella pneumoniae

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
UDP-galactopyranose Klebsiella pneumoniae
-
 UDP-galactofuranose
-
 ?
UDP-galactopyranose Escherichia coli
-
 UDP-galactofuranose
-
 ?

Organism

Organism UniProt Comment Textmining
Escherichia coli P37747
-
-
Klebsiella pneumoniae
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Klebsiella pneumoniae
-
 Escherichia coli

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
UDP-galactopyranose
-
 Klebsiella pneumoniae UDP-galactofuranose
-
 ?
UDP-galactopyranose
-
 Escherichia coli UDP-galactofuranose
-
 ?

Subunits

Subunits Comment Organism
dimer solution scattering experiments Escherichia coli

Synonyms

Synonyms Comment Organism
mutase
-
 Klebsiella pneumoniae
mutase
-
 Escherichia coli
UDP-galactopyranose mutase
-
 Klebsiella pneumoniae
UDP-galactopyranose mutase
-
 Escherichia coli

Cofactor

Cofactor Comment Organism Structure
FAD
-
 Klebsiella pneumoniae
FAD
-
 Escherichia coli
NAD(P)H or other reductants Klebsiella pneumoniae
NAD(P)H or other reductants Escherichia coli