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Literature summary for 5.4.99.7 extracted from

  • Taramino, S.; Teske, B.; Oliaro-Bosso, S.; Bard, M.; Balliano, G.
    Divergent interactions involving the oxidosqualene cyclase and the steroid-3-ketoreductase in the sterol biosynthetic pathway of mammals and yeasts (2010), Biochim. Biophys. Acta, 1801, 1232-1237.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 5.4.99.7

Activating Compound

Activating Compound Comment Organism Structure
additional information no protective action of steroid-3-ketoreductase towards OSC is necessary Homo sapiens
steroid-3-ketoreductase
-
 Saccharomyces cerevisiae

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
(S)-squalene-2,3-epoxide Homo sapiens
-
 Lanosterol
-
 ?
(S)-squalene-2,3-epoxide Saccharomyces cerevisiae
-
 Lanosterol
-
 ?
(S)-squalene-2,3-epoxide Saccharomyces cerevisiae SCY876 and BTY6-5-3
-
 Lanosterol
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Saccharomyces cerevisiae
-
-
-
Saccharomyces cerevisiae SCY876 and BTY6-5-3
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
NS-0 cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(S)-squalene-2,3-epoxide
-
 Homo sapiens Lanosterol
-
 ?
(S)-squalene-2,3-epoxide
-
 Saccharomyces cerevisiae Lanosterol
-
 ?
(S)-squalene-2,3-epoxide
-
 Saccharomyces cerevisiae SCY876 and BTY6-5-3 Lanosterol
-
 ?

Synonyms

Synonyms Comment Organism
Erg7p
-
 Homo sapiens
OSC
-
 Homo sapiens
OSC
-
 Saccharomyces cerevisiae
Oxidosqualene cyclase
-
 Homo sapiens
Oxidosqualene cyclase
-
 Saccharomyces cerevisiae