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Literature summary for 5.4.99.45 extracted from

  • Lecointe, F.; Namy, O.; Hatin, I.; Simos, G.; Rousset, J-P.; Grosjean, H.
    Lack of pseudouridine 38/39 in the anticodon arm of yeast cytoplasmic tRNA decreases in vivo recoding efficiency (2002), J. Biol. Chem., 277, 30445-30453.
    View publication on PubMed
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Cloned(Commentary)

Cloned (Comment) Organism
-
 Saccharomyces cerevisiae

Protein Variants

Protein Variants Comment Organism
D151A inactive mutant Saccharomyces cerevisiae

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
tRNA uridine38 Saccharomyces cerevisiae
-
 tRNA pseudouridine38
-
 ?
tRNA uridine39 Saccharomyces cerevisiae
-
 tRNA pseudouridine39
-
 ?

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae P31115
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
tRNA uridine38
-
 Saccharomyces cerevisiae tRNA pseudouridine38
-
 ?
tRNA uridine39
-
 Saccharomyces cerevisiae tRNA pseudouridine39
-
 ?

General Information

General Information Comment Organism
malfunction deletion of the PUS3 gene has an effect on the efficiency of the translation process. Reduced readthrough efficiency of each stop codon by natural nonsense suppressor tRNAs Saccharomyces cerevisiae