Literature summary for 5.4.99.39 extracted from

Kirby, J.; Romanini, D.W.; Paradise, E.M.; Keasling, J.D.
Engineering triterpene production in Saccharomyces cerevisiae-beta-amyrin synthase from Artemisia annua (2008), FEBS J., 275, 1852-1859.

Search for more literature for 5.4.99.39

Application

Application	Comment	Organism
synthesis	engineering of the sterol pathway in Saccharomyces cerevisiae for production of beta-amyrin. Expression of enzyme gene plus manipulation of 3-hydroxy-3-methylglutaryl-CoA reductase and lanosterol synthase in Saccharomyces cerevisiae leads to levels of 6 mg beta-amyrin per l of culture	Artemisia annua

Cloned(Commentary)

Cloned (Comment)	Organism
expression in Saccharomyces cerevisiae	Artemisia annua

Protein Variants

Protein Variants	Comment	Organism
additional information	functional expression in Saccharomyces cerevisiae results in production of beta-amyrin	Artemisia annua

Organism

Organism	UniProt	Comment	Textmining
Artemisia annua	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2,3-oxidosqualene	-	Artemisia annua	beta-amyrin	-	?

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Release 2023.1 (January 2023)