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Literature summary for 5.4.99.24 extracted from
- An indigenous posttranscriptional modification in the ribosomal peptidyl transferase center confers resistance to an array of protein synthesis inhibitors (2008), J. Mol. Biol., 380, 593-597.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
- |
Escherichia coli |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Escherichia coli | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 23S rRNA uridine955/uridine2504/uridine2580 | - |
Escherichia coli | 23S rRNA pseudouridine955/pseudouridine2504/pseudouridine2580 | - |
? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| RLuc | - |
Escherichia coli |
General Information
| General Information | Comment | Organism |
|---|---|---|
| malfunction | in the rluC- strain, susceptibility to some antibiotics increases dramatically. The most pronounced effects in comparison with the rluC+ control are observed with clindamycin (16-fold), linezolid (8-fold), and tiamulin (4-fold) | Escherichia coli |
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Release 2023.1 (January 2023)
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