Literature summary for 5.4.3.3 extracted from

Stadtman, T.C.; Tsai, L.
A cobamide coenzyme dependent migration of the e-amino group of D-lysine (1967), Biochem. Biophys. Res. Commun., 28, 920-926.

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Activating Compound

Activating Compound	Comment	Organism	Structure
mercaptan	e.g. 1,4-dimercaptothreitol required	Acetoanaerobium sticklandii

Inhibitors

Inhibitors	Comment	Organism	Structure
glycoprotein intrinsic factor	-	Acetoanaerobium sticklandii

Metals/Ions

Metals/Ions	Comment	Organism	Structure
K+	stimulation by monovalent cations, K+ or NH4+	Acetoanaerobium sticklandii
Mg2+	required	Acetoanaerobium sticklandii
NH4+	stimulation by monovalent cations, K+ or NH4+	Acetoanaerobium sticklandii

Organism

Organism	UniProt	Comment	Textmining
Acetoanaerobium sticklandii	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
D-alpha-Lysine	-	Acetoanaerobium sticklandii	2,5-Diaminohexanoate	-	?

Cofactor

Cofactor	Comment	Organism	Structure
ATP	required	Acetoanaerobium sticklandii
Cobalamin	required	Acetoanaerobium sticklandii
FAD	slight activation	Acetoanaerobium sticklandii

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Release 2023.1 (January 2023)