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Literature summary for 5.4.2.8 extracted from

  • Regni, C.; Tipton, P.A.; Beamer, L.J.
    Crystal Structure of PMM/PGM: An Enzyme in the Biosynthetic Pathway of P. aeruginosa Virulence Factors (2002), Structure, 10, 269-279.
    View publication on PubMed
Search for more literature for 5.4.2.8

Crystallization (Commentary)

Crystallization (Comment) Organism
crystal structure of the selenomethionine-substituted PMM/PGM at 2.2 A resolution, crystal structure of S108A mutant at 1.75 A resolution Pseudomonas aeruginosa

Protein Variants

Protein Variants Comment Organism
S108 crystal structure, 5% of wild-type activity Pseudomonas aeruginosa
S10V 5% of wild-type activity Pseudomonas aeruginosa

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ required for activity Pseudomonas aeruginosa

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
alpha-D-mannose 1-phosphate Pseudomonas aeruginosa PMM/PGM catalyzes the second step in alginate biosynthesis alpha-D-mannose 6-phosphate
-
 r

Organism

Organism UniProt Comment Textmining
Pseudomonas aeruginosa P26276
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
phosphoprotein active form of PMM/PGM is phosphorylated at Ser108 Pseudomonas aeruginosa

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
alpha-D-glucose 1-phosphate
-
 Pseudomonas aeruginosa alpha-D-glucose 6-phosphate
-
 r
alpha-D-mannose 1-phosphate
-
 Pseudomonas aeruginosa alpha-D-mannose 6-phosphate
-
 r
alpha-D-mannose 1-phosphate PMM/PGM catalyzes the second step in alginate biosynthesis Pseudomonas aeruginosa alpha-D-mannose 6-phosphate
-
 r

Synonyms

Synonyms Comment Organism
PMM/PGM
-
 Pseudomonas aeruginosa