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Literature summary for 5.4.2.6 extracted from

  • Barrozo, A.; Liao, Q.; Esguerra, M.; Marloie, G.; Florian, J.; Williams, N.H.; Kamerlin, S.C.L.
    Computer simulations of the catalytic mechanism of wild-type and mutant beta-phosphoglucomutase (2018), Org. Biomol. Chem., 16, 2060-2073.
    View publication on PubMed
Search for more literature for 5.4.2.6

Activating Compound

Activating Compound Comment Organism Structure
beta-D-glucose 1,6-bisphosphate
-
 Lactococcus lactis subsp. lactis

Protein Variants

Protein Variants Comment Organism
D10C inactive Lactococcus lactis subsp. lactis
D10C the mutant shows abolished catalytic activity Lactococcus lactis subsp. lactis
D10N inactive Lactococcus lactis subsp. lactis
D10N the mutant shows abolished catalytic activity Lactococcus lactis subsp. lactis
D10S inactive Lactococcus lactis subsp. lactis
D10S the mutant shows abolished catalytic activity Lactococcus lactis subsp. lactis
D170A inactive Lactococcus lactis subsp. lactis
E169A/D170A inactive Lactococcus lactis subsp. lactis
H20A inactive Lactococcus lactis subsp. lactis
H20Q inactive Lactococcus lactis subsp. lactis
K76A inactive Lactococcus lactis subsp. lactis
T16P inactive Lactococcus lactis subsp. lactis

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ required Lactococcus lactis subsp. lactis

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
beta-D-Glucose 1-phosphate Lactococcus lactis subsp. lactis
-
 beta-D-Glucose 6-phosphate
-
 ?
beta-D-Glucose 1-phosphate Lactococcus lactis subsp. lactis IL1403
-
 beta-D-Glucose 6-phosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Lactococcus lactis subsp. lactis P71447
-
-
Lactococcus lactis subsp. lactis IL1403 P71447
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
beta-D-Glucose 1-phosphate
-
 Lactococcus lactis subsp. lactis beta-D-Glucose 6-phosphate
-
 ?
beta-D-Glucose 1-phosphate
-
 Lactococcus lactis subsp. lactis IL1403 beta-D-Glucose 6-phosphate
-
 ?

Synonyms

Synonyms Comment Organism
beta-PGM
-
 Lactococcus lactis subsp. lactis