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Literature summary for 5.4.2.2 extracted from
- Streptococcus iniae phosphoglucomutase is a virulence factor and a target for vaccine developement (2005), Infect. Immun., 73, 6935 - 6944.
Application
| Application | Comment | Organism |
|---|---|---|
| drug development | the activity of the PGM gene of Streptococcus iniae is linked to a variety of structural and functional phenotypes that translate to dramatically decreased virulence in a model of fish meningoencephalitis | Streptococcus iniae |
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expression in Escherichia coli | Streptococcus iniae |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Streptococcus iniae | - |
- |
- |
| Streptococcus iniae K288 | - |
- |
- |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| additional information | - |
PGM activity decreases more than fivefold in mutant TnM2 compared to the wild type strain | Streptococcus iniae |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| D-glucose-1-phosphate | - |
Streptococcus iniae | glucose-6-phosphate | - |
? |  |
| D-glucose-1-phosphate | - |
Streptococcus iniae K288 | glucose-6-phosphate | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| PGM | - |
Streptococcus iniae |
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Release 2023.1 (January 2023)
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