Activating Compound | Comment | Organism | Structure |
---|---|---|---|
2,3-bisphosphoglycerate | - |
Saccharomyces cerevisiae |
Cloned (Comment) | Organism |
---|---|
overexpression in Saccharomyces cerevisae | Saccharomyces cerevisiae |
Crystallization (Comment) | Organism |
---|---|
crystal structure at 2.12 a resolution | Saccharomyces cerevisiae |
Protein Variants | Comment | Organism |
---|---|---|
A60S | 69% of wild-type activity | Saccharomyces cerevisiae |
E86Q | 1% of wild-type activity | Saccharomyces cerevisiae |
S11A | 4% of wild-type activity | Saccharomyces cerevisiae |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.43 | - |
3-phospho-D-glycerate | A60S mutant | Saccharomyces cerevisiae | |
0.47 | - |
3-phospho-D-glycerate | - |
Saccharomyces cerevisiae | |
0.71 | - |
3-phospho-D-glycerate | S11A mutant | Saccharomyces cerevisiae | |
1.1 | - |
3-phospho-D-glycerate | E86Q mutant | Saccharomyces cerevisiae |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
2-phospho-D-glycerate | Saccharomyces cerevisiae | - |
3-phospho-D-glycerate | - |
r |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Saccharomyces cerevisiae | P00950 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2-phospho-D-glycerate | - |
Saccharomyces cerevisiae | 3-phospho-D-glycerate | - |
r |
Synonyms | Comment | Organism |
---|---|---|
PGAM | - |
Saccharomyces cerevisiae |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
4.7 | - |
3-phospho-D-glycerate | E86Q mutant | Saccharomyces cerevisiae | |
20 | - |
3-phospho-D-glycerate | S11A mutant | Saccharomyces cerevisiae | |
370 | - |
3-phospho-D-glycerate | A60S mutant | Saccharomyces cerevisiae | |
530 | - |
3-phospho-D-glycerate | - |
Saccharomyces cerevisiae |