Any feedback?
Literature summary for 5.3.99.6 extracted from
- The crystal structure of Arabidopsis thaliana allene oxide cyclase: insights into the oxylipin cyclization reaction (2006), Plant Cell, 18, 3201-3217.
Crystallization (Commentary)
| Crystallization (Comment) | Organism |
|---|---|
| modeling of complexes with substrate 12,13-epoxy-9,11,15-octadecatrienoic acid and product 12-oxo-phytodienoic acid. Reaction is promoted by anchimeric assistance through a conserved Glu residue. The transition state with a pentadienyl carbocation and an oxyanion is stabilized by a strongly bound water molecule and favorable pi-pi interactions with aromatic residues in the cavity | Arabidopsis thaliana |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| vernolic acid | substrate analogue, competitive | Arabidopsis thaliana |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Arabidopsis thaliana | - |
- |
- |
Reaction
| Reaction | Comment | Organism | Reaction ID |
|---|---|---|---|
| (9Z)-(13S)-12,13-epoxyoctadeca-9,11,15-trienoate = (15Z)-12-oxophyto-10,15-dienoate | reaction is promoted by anchimeric assistance through a conserved Glu residue. The transition state with a pentadienyl carbocation and an oxyanion is stabilized by a strongly bound water molecule and favorable pi-pi interactions with aromatic residues in the cavity | Arabidopsis thaliana |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
