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BRENDA support

Literature summary for 5.3.99.5 extracted from

  • Albuquerque, M.G.; Rodrigues.C.R.; Bicca de Alencastro, R.
    Design of new potential 5-lipoxygenase inhibitors. Dual thromboxane synthase inhibitors, and thromboxane A2 receptor antagonists by AM1 (1995), Int. J. Quantum Chem., 22, 181-190.
No PubMed abstract available

Inhibitors

Inhibitors Comment Organism Structure
additional information design of new potential dual blocker which inhibits thromboxane synthase and antagonizes thromboxane A2 receptor Mammalia

Organism

Organism UniProt Comment Textmining
Mammalia
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Prostaglandin H2 i.e. PGH2 Mammalia thromboxane B2 + 12(L)-hydroxy-5,8,10-heptadecatrienoic acid
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