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Literature summary for 5.3.99.4 extracted from

  • Sasaki, Y.; Ochiai, T.; Takamura, M.; Kondo, Y.; Yokoyama, C.; Hara, S.
    Role of prostacyclin synthase in carcinogenesis (2017), Prostaglandins Other Lipid Mediat., 133, 49-52 .
    View publication on PubMed
Search for more literature for 5.3.99.4

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
Prostaglandin H2 Homo sapiens
-
 Prostaglandin I2
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
smooth muscle cell
-
 Homo sapiens
-
vascular endothelial cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Prostaglandin H2
-
 Homo sapiens Prostaglandin I2
-
 ?

Synonyms

Synonyms Comment Organism
PGI2 synthase
-
 Homo sapiens
PGIS
-
 Homo sapiens
prostacyclin synthase
-
 Homo sapiens

Expression

Organism Comment Expression
Homo sapiens the enzyme expression is downregulated in several types of cancer down

General Information

General Information Comment Organism
physiological function the enzyme is critical for the regulation of platelet aggregation and vascular tone Homo sapiens