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Literature summary for 5.3.99.4 extracted from

  • Smith, W.L.; DeWitt, D.L.; Day, J.S.
    Purification, quantitation, and localization of PGI2 synthase using monoclonal antibodies (1983), Adv. Prostaglandin Thromboxane Leukot. Res., 11, 87-92.
    View publication on PubMed
Search for more literature for 5.3.99.4

Application

Application Comment Organism
medicine formation of monoclonal antibodies against prostacyclin synthase Bos taurus

Inhibitors

Inhibitors Comment Organism Structure
13-hydroperoxylinoleic acid rapid inactivation of purified enzyme during incubation with prostaglandin H2 Bos taurus
9,11-Azoprosta-5,13-dienoic acid
-
 Bos taurus
monoclonal antibodies against prostacyclin synthase Bos taurus
prostaglandin H2 rapid inactivation of purified enzyme during incubation with prostaglandin H2 Bos taurus

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome
-
 Bos taurus
-
-
plasmalemma
-
 Bos taurus
-
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
52000
-
 x * 52000, SDS-PAGE Bos taurus

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Bos taurus

Source Tissue

Source Tissue Comment Organism Textmining
aorta
-
 Bos taurus
-
endothelium
-
 Bos taurus
-
smooth muscle vascular and nonvascular Bos taurus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Prostaglandin H2
-
 Bos taurus Prostaglandin I2 prostaglandin I2 ?

Subunits

Subunits Comment Organism
? x * 52000, SDS-PAGE Bos taurus