Any feedback?
Literature summary for 5.3.99.3 extracted from
- The inducible prostaglandin E synthase mPGES-1 regulates growth of endometrial tissues and angiogenesis in a mouse implantation model (2011), Biomed. Pharmacother., 65, 77-84.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | mPGES-1 is a therapeutic target for endometriosis | Mus musculus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Prostaglandin H2 | Mus musculus | - |
Prostaglandin E2 | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| endometrium | - |
Mus musculus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Prostaglandin H2 | - |
Mus musculus | Prostaglandin E2 | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| microsomal prostaglandin E synthase | - |
Mus musculus |
| mPGES | - |
Mus musculus |
General Information
| General Information | Comment | Organism |
|---|---|---|
| malfunction | the expression of vascular endothelial growth factor A is significantly reduced in mPGES-1-deficient endometrial tissues implanted into mPGES-1-deficient mice at days 14 and 28 | Mus musculus |
| physiological function | mPGES-1 regulates growth of endometrial tissues and angiogenesis | Mus musculus |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
