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Literature summary for 5.3.99.3 extracted from

  • Takemiya, T.; Matsumura, K.; Sugiura, H.; Maehara, M.; Yasuda, S.; Uematsu, S.; Akira, S.; Yamagata, K.
    Endothelial microsomal prostaglandin E synthase-1 exacerbates neuronal loss induced by kainate (2010), J. Neurosci. Res., 88, 381-390.
    View publication on PubMed
Search for more literature for 5.3.99.3

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Mus musculus
-
brain
-
 Rattus norvegicus
-
hippocampus
-
 Mus musculus
-
hippocampus
-
 Rattus norvegicus
-
venous endothelial cell
-
 Mus musculus
-
venous endothelial cell
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Prostaglandin H2
-
 Mus musculus Prostaglandin E2
-
 ?
Prostaglandin H2
-
 Rattus norvegicus Prostaglandin E2
-
 ?

Synonyms

Synonyms Comment Organism
microsomal prostaglandin E synthase-1
-
 Mus musculus
microsomal prostaglandin E synthase-1
-
 Rattus norvegicus
mPGES-1
-
 Mus musculus
mPGES-1
-
 Rattus norvegicus

Expression

Organism Comment Expression
Mus musculus microinjection of kainic acid induces mPGES-1 in venous endothelial cells but not in neurons or astrocytes up
Rattus norvegicus microinjection of kainic acid induces mPGES-1 in venous endothelial cells but not in neurons or astrocytes up

General Information

General Information Comment Organism
malfunction mPGES-1-deficient mice exhibit significantly less neuronal loss induced by kainic acid Mus musculus