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Literature summary for 5.3.99.2 extracted from
- Comprehensive evaluation of the binding of lipocalin-type prostaglandin D synthase to poorly water-soluble drugs (2017), Mol. Pharm., 14, 3558-3567 .
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in Escherichia coli BL21(DE3) cells | Homo sapiens |
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| C65A/C167A | inactive | Homo sapiens |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| atovaquone | - |
Homo sapiens |  |
| imatinib | - |
Homo sapiens | |
| lapatinib | - |
Homo sapiens | |
| nilotinib | - |
Homo sapiens | |
| telmisartan | - |
Homo sapiens | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Prostaglandin H2 | Homo sapiens | - |
Prostaglandin D2 | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | P41222 | - |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| glutathione Sepharose column chromatography and Superdex 75 gel filtration | Homo sapiens |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Prostaglandin H2 | - |
Homo sapiens | Prostaglandin D2 | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| L-PGDS | - |
Homo sapiens |
| lipocalin-type prostaglandin d synthase | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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